In general, with neurodegenerative disorders like Alzheimer's disease , "what you see is what you get." In other words, the pattern by which things have changed over the last six months is the best indicator of how they'll change over the next six months. Alzheimer's disease operates on a "season by season basis." Most family members of people with Alzheimer's disease can think of how things are now, say in the winter, and how they've changed in comparison to the way they used to be in the fall, prior to that, the way they used to be in the summer. It is unusual for people to say, everything being equal, how things might have changed from one week to the next or from one month to the next. If there was rapid progression, this would signal that there could be something else going on that needs to be evaluated.