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Sleep Disturbances | What's Happening in the Brain

There are a number of fascinating links between sleep behaviour and Alzheimer's disease . For example, melatonin , which helps set the body's clock and maintain sleep, has been reported to be specifically disrupted in Alzheimer's disease. (Wu YH, Swaab DF. The human pineal gland and melatonin in aging and Alzheimer's disease. J Pineal Res. 2005;38:145-52).

Sleep can also be disrupted following treatment with anti-dementia drugs, including donepezil. Often, however, switching from taking the drug at night to taking it in the morning can alleviate that problem. (Jackson S et al., "The safety and tolerability of donepezil in patients with Alzheimer's disease". Br J Clin Pharmacol. 2004;58 Suppl 1:1-8.)

See Also:
Symptom Library > Personality Changes > Restlessness
Symptom Library > Behaviour > Wandering
Symptom Library > Personality Changes > Low Mood
Symptom Library > Behaviour > Delusions and Paranoia
About Dementia > Working with your Doctor > Specialist Referrals
About Dementia > Types of Dementia > Delirium
About Dementia > Treatments for Dementia > Exercise
About Dementia > Treatments for Dementia > Exercise Program
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Last updated January 13, 2019
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