What's Happening in the Brain
To be socially engaged with other people is to have some understanding of what they are thinking. In psychology, this ability is termed 'theory of mind' and is a frontal lobe function. The neurobiology is described in DT Stuss and V Anderson. The frontal lobes and theory of mind: developmental concepts from adult focal lesion research. Brain Cogn. 2004;55:69-83. A specific account of theory of mind in Alzheimer's disease can be found in Gregory C, et al., Theory of mind in patients with frontal variant frontotemporal dementia and Alzheimer's disease: theoretical and practical implications. Brain. 2002;125(Pt 4):752-64.